PresentationPrinciple
A DNA microarray is a multiplex technology used in molecular biology.
It consists of an arrayed series of thousands of microscopic spots of DNA oligonucleotides, each containing picomoles (10−12 moles) of a specific DNA sequence, known as probes (or reporters).
These are used to hybridize a cDNA or cRNA sample (called target) under high-stringency conditions. Probe-target hybridization is usually detected and quantified by detection of fluorophore-, silver-, or chemiluminescence-labeled targets to determine relative abundance of nucleic acid sequences in the target.
Since an array can contain tens of thousands of probes, a microarray experiment can accomplish many genetic tests in parallel. Therefore arrays have dramatically accelerated many types of investigation.
Services
ArraySud can provide the following services : probe design, experimental design, hybridization and analysis.
Contacts : Cécile Fairhead and Karine Budin